Persistence or Relapse of Lyme Disease
Despite
"Appropriate" or "Conventional" Antibiotic Therapy
Lyme disease is a serious bacterial infection caused by a tick bite and
affects humans and animals.
Table of Contents
Persistence or Relapse of Lyme Disease - A Bibliography with Highlighted Full Abstracts
Medical and scientific articles on the persistence or relapse of Lyme disease
Other articles on the persistence or relapse of Lyme disease
Resources for persistence of relapse of Lyme disease
Also see
For more information on Lyme disease
Persistence or Relapse of Lyme Disease Despite "Appropriate" or
"Conventional" Antibiotic Therapy
A Bibliography with Highlighted Full Abstracts
The web pages at the following links contain citations and highlighted abstracts for medical and scientific articles pertaining to the persistence or relapse of Lyme disease from the National Institutes of Health (NIH), National Library of Medicine (NLM) MEDLINE database.
Persistence or Relapse of Lyme Disease
despite "appropriate" or "conventional" antibiotic therapy -
A bibliography with highlighted full abstracts
Reasons for the survival of Lyme disease bacteria (cystic forms, blebs, L-forms, etc.) - A bibliography of with highlighted full abstracts
Medical and scientific articles on the persistence or relapse of Lyme disease
["Dr. Fried has seen B burgdorferi persist in the GI tract despite multiple rounds of antibiotics over many years."]
Clinical Aspects of LD: Dermatologic, Cardiac, GI, and Gestational, 14th ISC on LD, 23 Apr 01
B. burgdorferi Infection after Antibiotic Treatment, Straubinger et al., JID, Apr 2000
Infection With Lyme Disease Spirochete May Linger in Antibiotic-Treated Dogs, Reuters, Apr 00
Persistent Lyme Disease responds to additional antibiotic therapy in an uncontrolled trial (6/2000)
Repeated Antibiotic Treatment in Chronic Lyme Disease, Fallon et al., JSTD, Fall/Winter 1999
Lyme Disease and the Clinical Spectrum of Antibiotic Responsive Chronic Meningoencephalomyelitides, Liegner, et al., JSTD, Fall/Winter 1997
["Despite aggressive IV and oral antimicrobial treatment, B. burgdorferi may persist in sequestered areas of the body such as bone marrow."]
Bone Marrow as a Source for Borrelia burgdorferi DNA, Fein, et al., JSTD, Fall/Winter 1997
Two Lessons From the Canine Model of Lyme Disease:...and Persistence After Antibiotic Treatment, Straubinger, et al., JSTD, Spring/Summer 1997
Eighth Annual Scientific Conference on Lyme Borreliosis, Banerjee, JSTD, December 1995
["Chronic persistent symptoms after treatment for Lyme disease (LD) are common."]
Neuroborreliosis in Texas, Goldings, JSTD, September 1995
["It is possible that protracted symptoms may be a function of persistent infection due to Bb."]
Persistent PCR Positivity in a Patient Being Treated for Lyme Disease, Keszler, JSTD, Sep 1995
["The presumption that 1 month of treatment should cure Lyme disease appears now to be incorrect, as many practitioners are finding..."]
Special Editorial, Donta, JSTD, September 1995
["These two cases suggest that despite lengthy courses of both intravenous and oral antibiotics, Borrelia burgdorferi may persist."]
Letters to the Editor: Persistence of Borrelia burgdorferi Despite Antibiotic Treatment, Palmas, JSTD, December 1994
Fighting Back: How B burgdorferi Persists, 14th ISC on Lyme Disease, 23 Apr 01 [re supressing or avoiding the immune system]
Detection of Borrelia DNA...as Evidence of Persistent Lyme Disease, JSTD, Spring/Summer 2000
Dissemination of Borrelia burgdorferi After Experimental Infection in Dogs, Chang, et al., JSTD, March 1996
Guest Editorial: B. burgdorferi-Seek and Ye Shall Find Expanding the Envelope, Liegner, JSTD, December 1994
Other articles on the persistence or relapse of Lyme disease
["In a few patients who are treated for Lyme disease, symptoms of persisting infection may continue or recur, making additional antibiotic treatment necessary."]
CDC: Lyme Disease
["symptoms persist despite appropriate treatment (3,4). Causes could include persistent spirochetosis (5),"]
CDC: Imported Malaria Assoc with Malariotherapy of Lyme Disease -- NJ
["the Lyme disease spirochetes...may become enveloped in lymphocyte membranes, effectively avoiding immune recognition and destruction."]
NIH/NIAID: The Rocky Mountain Laboratories Microscopy Branch
["It has become increasingly apparent that the Lyme disease spirochete, Borrelia burgdorferi, may persist in some patients for years."]
Dr. Steere's Letter Regarding Persistent B. burgdorferi Infection
Information Regarding the Columbia Persistent Lyme Encephalopathy Study, Dr Fallon's study
Pain persists in treated Lyme patients, Michael Lasalandra, Boston Herald, 22 Dec 99
Resources for Persistence of Lyme disease
Persistent Lyme Disease Infection Reference List - 60 citations
Historical Observations of Spirochetal Cysts and L-Forms - lots of citations
Bibliography for Persistent Lyme disease - Lyme Alliance - 57 citations
Medscape Clinical Full-Text: Lyme disease AND (persist* OR relapse) - 110 on 15 Jul 01
Medscape News: Lyme disease AND (persist* OR relapse) - 50 on 15 Jul 01
Google Search: "persistence of Lyme disease" - 31 on 15 Jun 01
Google Search: "relapse of Lyme disease" - 79 on 15 Jun 01
Google Search: intitle:Lyme persistence OR persist - 485 on 15 Jul 01
Google Search: intitle:Lyme relapse NOT persistence NOT persist - 204 on 15 Jul 01
Google Search: Lyme disease burgdorferi persistence OR persist - 1380 on 15 Jul 01
Google Search: Lyme disease burgdorferi relapse NOT persistence NOT persist - 377 on 15 Jul 01
Google Search: Lyme disease burgdorferi relapse - 660 on 15 Jul 01
Also see:
Long-Term or Repeated Antibiotic Therapy for Lyme Disease
If Lyme disease is so easily cured why did Dattwyler ...? - An Annotated Bibliography
For more information on Lyme disease see:
Lots Of Links On Lyme Disease
Comments or questions concerning this page should be directed to
Art Doherty.
Last updated on 17 July 2001 by
Art Doherty
Lompoc, California
doherty@utech.net