*      When Irwin Tessman, Ph.D., professor of biological sciences at Purdue University, requested of Dr. Byrd that Dr. Tessman be allowed to review the raw data that went into the study, he was refused.  Since Dr. Byrd’s claim is one of the supernatural, it would seem appropriate that all aspects of the study be reviewed by independent investigators.
*      The Degree of obvious religiosity communicated by Dr. Byrd raises doubts that he could be completely objective on a scientific investigation of prayer, something that he deeply believes is effective.  Under “Acknowledgments” at the end of the paper, he writes: “I thank God for responding to the many prayers made on behalf of the patients.”
     The second study that appears to meet the “gold standard” for scientific studies is “A Randomized, Controlled Trial of the Effects of Remote, Intercessory Prayer on Outcomes in Patients Admitted to the Coronary Care Unit” published in the October 25, 1999 edition of the Archives of Internal Medicine.  The investigators were William S. Harris, Ph.D., plus eight others of the Mid America Heart Institute.  The study was conducted at Saint Luke’s Hospital, Kansas City, Missouri, a private, university-associated hospital.
     “The purpose of the present study was to attempt to replicate Byrd’s findings by testing the hypothesis that patients who are unknowingly and remotely prayed for by blinded intercessors will experience fewer complications and have a shorter hospital stay than patients not receiving such prayer,” admitted the investigators.
     The intercessors (five to pray for each patient compared to three to seven in Byrd’s study), were to pray for “a speedy recovery with no complications” plus “anything else that seemed appropriate to them.” 1013 patients were randomized, 484 to the prayer group and 529 to the usual care group.  After removal of those patients who spent less than 24 hours in the CCU (prayer was not started until 24 hours after admission), 524 remained in the usual care group and 466 in the prayer group (a high dropout rate).
     A list of events after entry into the study was compiled, much like the one in the Byrd study, but with 34 events instead of the 26 in the Byrd study.  Again, a scheme was devised to evaluate the overall hospital course, a totally new and untested system, but different from the also new and untested one devised by Byrd.  The Harris study scheme was called the Mid America Heart Institute Cardiac Care Unit (MAHI-CCU) Scoring System, and its criteria are presented in “Table 1” of his paper.
     The only finding in the Harris study that indicated the prayer group out-performed the control group was in using the MAHI-CCU Scoring System and then only at a probability level of (.04), a figure very close to the cut-off level of (.05).
     The Harris study is a much better study than the Byrd study because the number of patients is larger, it appears to be completely blinded, and the degree of religiosity of the investigators appears to be lower (although Dr. Harris supposedly supports the idea of “intelligent design”).  Nevertheless, scientific investigators have noted flaws:
1)      As already noted, the MAHI-CCU Scoring System has never been previously scientifically validated.  Without such validation, any result produced by it is subject to question.
2)      The much higher dropout rate in the first 24 hours in the prayer group is a very serious criticism of the study. The statistical probability that this finding would appear by chance is (.001), or 1 chance in a 1000, a statistically very significant 
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