- John Billingsley as Doctor Phlox, Chief Medical Officer
- Linda Park as Ensign Hoshi Sato, Communications Officer
- Scott Bakula as Captain Jonathan Archer
- Connor Trinneer as Commander Charles "Trip" Tucker III, Chief Engineer
- Dominic Keating as Lieutenant Commander Malcolm Reed, Armoury Officer
- Jolene Blalock as Subcommander T'Pol, Science Officer & First Officer
- A.T. Montgomery as Lieutenant Travis Mayweather, Helmsman
Porthos, Archer's canine companion (he's sooooo cute!)
Crewman Elizabeth Cutler
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