Running on a Full Bladder
To go or not to go? Every sim has to go at one time or the other. To keep your body and emotional well-being and avoid the dreaded Red Diamond Syndrome, emptying your bladder will help you on your way to happiness.

Drinking and eating will make your bladder full, so make sure you visit the bathroom after meals or you will be embarrassed.

Make sure you have more than one bathroom; this will allow you to relieve yourself if the other toilet is in use. Since you spend a lot of time on the toilet you should at least be comfortable.  Be sure to check out the stats of the toilet before buying it, some toilets are specially designed to be more comfortable than others. Also, buying a toilet with an automatic flush system will keep your bathroom clear of those embarrassing clogs and messes. 

Since emptying your bladder is so simple and easy, we need not spend a lot of time on the subject.